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Julyne's Beauty Blog

By Julyne Derrick, About.com Guide to Beauty since 2005

Why I Love Retin-A & Will Never Ever Stop Using It

Monday December 17, 2007
At age 35, my skin has never looked better. It's dewy, clear and pretty flawless. Usually this time of the year, I'm looking a bit ashy, but this fall I started using Retin-A. My goodness. I'm not stopping.

I learned about Retin-A years ago when a dermatologist prescribed it to a co-worker. At the time I thought it was odd my friend was using pimple lotion to look young, but her skin was as pristine as Nicole Kidman's. Later, another friend told me it was her beauty secret (and she looks 10 years younger than she is). Since then, I've read nothing but good things about vitamin A derivatives (Retin-A, Renova, Micro Retin-A), with many dermatologists going so far as to call them a miracle product. It's the only medicine on the market that's actually proven to boost collagen production, which decreases with age. I suggest it to all my friends, most of whom look at me as if they don't really believe me. I think the fact that you can't get it over-the-counter scares them. At some point, I'm going to compile all the dermatologists' comments that I've collected over the years to prove my point. But in the meantime, I'm never giving this stuff up. Ever.

So how to get it? In the U.S. it's prescription only. You can buy Renova (a version of Retin-A) from several vendors online.

Comments

December 18, 2007 at 9:47 am
(1) lily a. says:

Hello there, I’ve been prescribed with some Retin-A since I went for a chemical peel for my face. I have had good results of Retin-A. My skin is glowy and pimples slough off easily when I scrub them away. However, I’ve been told that continous use of Retin-A (say maybe for over 3 months) will make the skin weak and make it quite sensitive to dust particles, the harmful UV rays and dirt. Do you think that using Retin-A continously through the year will do this damage?

December 19, 2007 at 7:08 pm
(2) Karen says:

I have some, but am not sure how to use it, will it help with crows feet?

December 20, 2007 at 5:15 pm
(3) Dwala, owner Body Moose Skin Care says:

Retin-A is not a department-store face cream safe for (most) everyone; it is a variable-strength prescription medication.

Please Google “Retin-A neurologic toxicity” if you feel certain it is harmless. (It describes a 39-year old woman who apparently had a connection between NEEDING A WALKER and Retin-A.)

Specific questions are best addressed to physicians.

Retin-A can be wonderful, but it is not a “one-size fits all” product. This is definitely a YMMV!

Stay beautiful and safe, everybody! :o )

December 24, 2007 at 12:55 pm
(4) cyn says:

1. No–that’s steroid creams that weaken (thin) the skin. Retin-A makes the collagen layer thicker. I have used it for decades & look way younger than my peers.(But yes, you MUST wear sunscreen!)
2.Yes it helps with crows feet–use a tiny amount (a pea-sized dot for your whole face) & keep it an inch away from your eyes. It’s going to be reddish & peeling at first. Give it a few weeks for your skin to adjust.

December 24, 2007 at 2:17 pm
(5) Catherine says:

Where do you buy your Retin-A?

December 24, 2007 at 2:26 pm
(6) shannon says:

I used Retin A years ago for cyctic acne- stopped some years ago when the Rx ran out and my insurnace would not cover the cost, even if prescribed by
an MD. Thought I would need anothe prescription, but would really appreciate knowing where to get Retin OTC. Also what strength (%) do you all use and in creme or gel? Thank you

December 24, 2007 at 3:15 pm
(7) JUDY K. says:

HI,
As far as I know, at least in Chicago, you do need a prescription from a Dr. to get retin A. I am 51 & have used it for yrs. Everyone always tells me that I look much younger. I have not had any problems using it. My skin is much better using it then before. I did have some acne. Nothing serious, but this is why I started to use it. My husband does not believe it is the retin A that keeps my face young looking. He just thinks it is good genetics from my parents.

The only problem I have encountered was that the ins. always covered the cost. But when I turned 50 they told me they stop paying for it. That really bothered me. I checked into it too. It seems that they don’t think women get any acne after a certain age. Then it is considered a cosmetic product. The retin A is rather expensive. But to me it is worth it. I won’t say that it is perfect but it is close. If a person has deep wrinkles & starts to use it, I don’t think that it will get rid of that. From what I know you have to use it for yrs. But it is never to late to start to use it. I want to tell everyone to have a nice Christmas & a healthy, happy New Yr.! Judy K. Chicago.

December 24, 2007 at 3:44 pm
(8) Mary says:

I’m 51 and use Renova, and my skin is in great shape. It doesn’t seem to be strong enough for crows feet though and never seems to get that area dry/flaky like it does the other parts of my face. How would you compare Renova and Retin A? BTW I just discovered Weleda cream for rough skin that I put on sometimes and it is amazing!

December 24, 2007 at 4:05 pm
(9) beauty says:

I think Renova is a milder version of Retin-A and purported to be very effective. Unfortunately, the US medical system is wonky, so it may be difficult to get a prescription, which is why I advise getting it over the counter when out of the country. Unfortunately, I don’t know of any Mexican Websites that will sell it to you. I don’t stockpile because these products supposedly have an expiration date one should stick to and it takes forever to get through just one tube.

December 24, 2007 at 4:18 pm
(10) marica schembbi says:

Hi-never heard of this product, is it possible to have in Malta?

December 24, 2007 at 6:58 pm
(11) KLM says:

In response to comment #3, the key to that case was the fact the patient had a history of Hep C, which obviously impairs the liver’s ability to flush toxins. The patient had probably been well advised about the hazards of taking supplements and medications which were fat-soluble (and therefore could reach toxic levels more easily since her liver isn’t functioning properly, anyhow)–yet likely had not associated the impact of using a topical agent, which is still metabolized through the liver in the end. I think people who have normal functioning livers have much less to worry about where such issues are concerned, although I would suggest if anyone drinks heavily, they have a liver-function test done prior to using such products daily.

December 24, 2007 at 9:07 pm
(12) Rajni says:

Ilove retin A I have been using Retin for 15 years Im 52 years old people never beleive my age they think Im in my 40s, for the past few years I’ve been using Retin A Micro, Its great!! I will never stop using it.

December 25, 2007 at 7:18 am
(13) sara says:

what about strech marks ..?can retin A do something ?

December 26, 2007 at 12:11 am
(14) Penny says:

I have been using Retin A- cream, 0.05% for about 8 years now. I love my skin and get complimented always that I look much younger than I am. I just turned 59 no one believes me. They think my daughter and I are sisters.

Be careful… you don’t need to use a lot.just a pea-sized dot is enough. The only difference between Renova & Retin A is that Renova has moisturizer in it. You can add a bit of your own to the Retin-A. It has always been my secret. Although they tell you not to put it near your eyes.. I put it on the sides of mine and have decreased the crow’s feet. I LOVE RETIN-A !! You must use it everyday.. If you don’t, you will not get the best results. Wait until 3 months (be patient and use it correctly… more is not better), and you won’t believe the difference.
And no, I have no financial interest in the product (I wish I did). It also helps make pre-cancerous spots disappear in time. Good luck everyone… Hope it makes you look younger also…

December 26, 2007 at 2:31 pm
(15) Martha says:

Okay,Now, I want this stuff:) So WHERE do we get it in the states??

December 26, 2007 at 2:51 pm
(16) Kathleen says:

I use the Renova, you need a prescription in the US and can then obtain it at any pharmacy. had a pre-cancerous skin lesion removed and was prescribed this after – it works well.

December 27, 2007 at 7:08 pm
(17) Sharron says:

Hi,
I use to use Retina but no longer have insurence. Has anyone ever ordered from on-line Canadian Pharmacy? I really want to get some again! Please let me know
Thanks

December 28, 2007 at 9:18 pm
(18) Kim says:

If this improves elasticity and collegen, then why cant you put it on that thin sin below your eyes?

December 29, 2007 at 12:28 pm
(19) shannon says:

Read the fine print on the Canadian pharmacy websites- I believe that they may get their product from sources outside Canada and certainly not from the US. You may want to be sure it is coming from a reliable source.

December 29, 2007 at 12:30 pm
(20) shannon says:

In my case I used Retin A when it first came out for acne and used it for years afterward. Stopped a few years ago as the med expired and now I can’t get an Rx from my derm since he doesn’t think I need it since I no longer have acne.(I’m 54 and can use all the help I can get). Has anyone an ideas how to get an Rx from anyone other than their derm? Thanks.

January 2, 2008 at 7:01 pm
(21) beauty says:

Some more info on Retin-A: If you are getting a prescription, ask your doc about Renova, or Retin-A Micro. These are versions of Retin-A that were created to combat wrinkles.

It’s best not to use it near the eyes or mouth. So no-go on crow’s feet, ladies. Do not use product if you are breastfeeding, pregnant or thinking about becoming pregnant while on a vitamin A derivative. Vitamin A is harmful to unborn children. You should wear UV protection in the form of sunscreen and/or hats, so if you live in a sunny climate, be advised that your skin will be extra-sensitive to sun.

January 5, 2008 at 8:21 am
(22) Jeanne says:

You can find Retinol Cream (Vitamin A – 100,000 IU/ounce) in 2 oz. jars from Puritans Pride or vitamins.com for under $10.

January 5, 2008 at 1:12 pm
(23) beauty says:

In regards to Jeanne’s comments, I would be careful purchasing no-name brand vitamin-A derivatives from Puritan’s Pride. You can’t be sure of the product and unless you have researched the ingredients and the company, you’re better off with real Renova/Retin-A/Micro Retin-A. You can purchase Renova or Retin-A online through pharmacies in other countries. This is how I bought Anthelios sunscreen before it came to the US.

January 6, 2008 at 10:05 am
(24) Jeanne says:

With all due respect to Beauty and your expertise, Puritan’s Pride IS NOT a “no-name” product. I have used their Retinol A Cream for many years, with fantastic results, receiving many compliments of how smooth my 55-year-old facial skin feels and looks, with little or no wrinkles, crows feet, etc. They are a HUGE company in NY, and are one of the largest sellers of vitamins & supplements in the country. Yes, their Retinol A Cream is NOT a brand name like Renova or Retin-A, but it is available w/o a Rx, or having to go overseas to get an Rx. How sure can anyone be with an Rx product from an overseas pharmacy, manufactured by what company in what country, obviously NOT overseen by the FDA. If the brand name product from an overseas pharmacy is bad….will you get a refund? With all the problems recently found in toys and other products from overseas, I would quite frankly, be very scared putting a product on my skin that comes from where…China, India, or some 3rd world country with NO oversight? Puritan’s Pride offers a Money Back Guarantee, a company I can contact right in NY. In the end, the product I use works on me, is readily available w/o an Rx from a reputable US company, and because it is not a highly advertised “brand name”, the price is inexpensive. The ingredients are printed right on the label, and if I’m not mistaken, can be viewed prior to purchase using their website. As a matter of fact, I am ordering some today, as they have a sale going on…Buy 2, get 3 FREE, so I will get 5 – 2oz. jars for $19.90 + S&H, for a total of under $24!!

January 6, 2008 at 6:55 pm
(25) beauty says:

Hi Jeanne,
It’s awesome that you have found an anti-aging product that you adore and for such a great price.

But let me do a better job of explaining my point, as I’ve done some research on this and I do not want to steer my readers wrong.

There is a big difference in Retin-A and over-the-counter vitamin A products. Retin-A contains tretinoin, proven much more effective in treating wrinkles than Retinol, the main ingredient in Puritan’s Pride and most OTC products (see Retinol vs. Retin-A http://www.smartskincare.com/smartchoices/myths/myth_retinol_retina.html see also this article comparing the two http://www.paulaschoice.com.au/learn/article.asp?ID=28&PAGETYPE=ART&REFER=SKIN).

What happened is many companies tried to ride the hype of Retin-A when it came out. There are dozens and dozens of Vitamin A products on the market. But the facts are, they just aren’t as effective. The articles above go into extensive detail why. Simply put, they don’t contain tretinoin. If you look at your ingredient list, you’ll notice it’s missing tretinoin.

While you’re right that you have to know what you’re buying when you buy from Canada or Mexico, if you want the results that you’d get from Retin-A, then you need to buy Retin-A (or Renova or Retin-A Micro). You are simply not going to get the same results from an OTC vitamin A product.

Julyne

January 7, 2008 at 1:30 pm
(26) Penny says:

Hi, this is Penny with my 2 cents again. I definitely agree with Julyne. I have tried OTC products and there is no comparison! And yes, I do use it right under my eyes and on the sides of my eyes to eliminate crows feet. In my opinion, you are advised to “omit” those areas as well as your mouth because it could burn! I am just very careful after applying it and do not rub my eyes or go to bed immediately.
I am older than most of you responding (59) and I can tell you that many people think I had some “work” done on my face.
Most any dermatolgist will give you a script for it. However, my regular doc does also. He knows it is important to me and thankfully, I just have a small co-pay.
I used to have lots of freckles and I have none left. My skin is smooth, clear and wonderful. I wish the rest of me looked as good.lol
The best of luck to all who try it. Just remember, more is not better. Pea-sized is plenty and add a bit of moisturizer if using the Retin-A. I use the 0.05 cream.
You will love the feel of your face within 3 months of daily use.
Sorry to be verbose but I just LOVE IT !!
Penny :-)

January 9, 2008 at 10:19 am
(27) Brenda says:

I have Puritan’s Pride Vitamin A also. They are a very reputable company and have many excellent products.

January 9, 2008 at 10:25 am
(28) Brenda says:

I am 56 years old and was told just the other day, by an 18 year old that I look like I am 28!! But in all fairness, I started preparing for this when I was in my 20’s. The trick is to use anti-aging products before you get wrinkles. This makes it harder for them to peep through and surprise you one morning when you look in the mirror. Whatever you use, use it early!!!

January 15, 2008 at 10:09 am
(29) Judi says:

Listen to PENNY!!She knows what she is taking about, if it doesn’t contain TRETINOIN your not getting precsription strength! Consult a dermotologist he will tell you the same.
We all have tried so many products and when I new one comes out, we want to believe THIS will be the one.
The word you must look for is “TRETINOIN”
A great website some of you would really enjoy is Paula Begoun(I think I have spelled her last name right)Look it up she will tell you exactely about cosmetic ingredients.

March 8, 2008 at 9:54 pm
(30) bethany says:

I am a long-time Retin-A/Renova user, and nothing OTC compares to the Rx strength. The best drugstore OTC I have found is Neutrogena (usually the closest to pharmaceutical grade). I have ordered my Rx versions from medsmex.com for at least 7 years with no problems. However, Julyne said “It’s the only medicine on the market that’s actually proven to boost collagen production”…that may be true for “medicines” but there is a “non-medicine” option that should be considered. Copper peptides consistently outperform both Retinoic Acid and Vit C for building collagen in clinical studies. Not all copper peptides are the same…look for 1st generation peptides licensed by ProCyte (Neova, Neutrogena Visibly Firm), or the stronger, more stable 2nd generation copper peptides by Skin Biology (developed by the same guy that patented the 1st gen peptides and started ProCyte). Copper Peptides must be worked into slowly though, but are extremely effective in skin remodeling. I am now using both, and seeing great success.

March 8, 2008 at 10:09 pm
(31) beauty says:

Bethany is correct about copper peptides. The CP apparently is great coupled with Retin-A products, reducing irritation. Check out this article for more information: http://www.smartskincare.com/treatments/topical/copper.html

March 11, 2008 at 8:40 pm
(32) Susan Garnett says:

This will be my first time using Retin-A. I am 60 and the lines in my face are starting to show. I live in Mexico, so I can buy it over the counter, but I need to know what stength. I know to add a pea size amount to my moisturizer for easier coverage. I also need to know whether to apply it once or twice daily. Can I also use a self-tanning product at intervals? Thanks!!!!

March 12, 2008 at 12:31 pm
(33) beauty says:

Hi Susan, there are two types, .025 and .05 (or is it .25 & .5?) anyway, I use the .05. Apply once, at night before you go to bed. Rinse face in the morning. If you have sensitive skin, opt for the lighter (.025) and apply once every other night. Yes, you can use self-tanners, but it’s very, very important that you also wear sunscreen and stay out of the sun as much as possible. I’d advise a hat.

May 18, 2008 at 12:01 pm
(34) r says:

Can you use Retin-A foer wrinkles,with any
other cream,Use retin a in the night time,
then use a diffrent face cream in the daytime?

May 19, 2008 at 1:20 pm
(35) Heather Dawn says:

I am 33 and I have been using Retin -A .05 for over 3 months now for acne and my skin is actually worse. The break outs are arger, redder and deeper and the pores around my nose are larger and redder.

I know that it said it may get worse before better but does this sound familiar to anyone who has been using this product for a long time???

May 19, 2008 at 2:48 pm
(36) JaneD says:

Hi – I have used Retin-A off and on since my 20s and I am so thankful! I DID NOT use it during pregnancy or while I was nursing and so I have gone through the readjustment period more than once. Here are some tips:

1 – It does take at least 3 months to get through the red peeling skin and breakouts. I know those times are tough, but bear with it.

2-make sure your face is DRY before applying at night (as the instructions state – wait about 20-30 mins. before applying after you have washed your face)

3-keep the product away from the creases around your nose and your hairline and only use a PEA-SIZED amount — more is NOT better — it will irritate your skin much worse. I take a pea-sized dot on my index finger and dot the product on my forehead, chin, nose, and cheeks, then blend.

4 – If you are experiencing a lot of irritation apply the product every other night until the irritation calms down. I also put a little Jojoba oil in with my cleanser (Cetaphil) and pat some on my face (with water) to calm down the irritation (you can get pure jojoba oil at most health stores). You might also try a little green tea or chamomile tea splashed on your face if you can tolerate those things. Ask your dermatologist for a moisturizer or another product you can use to manage the dry skin and so forth.

5 – You MUST use a sunscreen (don’t trust your foundation to do the job either) — protect the investment you are making in your new, great skin!

6 – If you can tolerate it — dot some on your neck and decollete.

7 – If it has been over 3 mos. and your face is still irritated (and you are not making the common mistakes I mentioned above) talk to your dermatologist. Perhaps you need a different strength or to use the Micro Gel rather than the original cream formulation.

This is a good product with results worth all the effort. In a few months you will be SO HAPPY that you stuck with it! I have enlarged pores, blackheads and breakouts (and I’m 40 now) — all are significantly improved to the point that I hardly need any moisturizer or makeup!!

Last, but not least, I order my products from Granville Pharmacy in Canada. I have used them for the past 3 years without incident – I highly recommend them.

Hope this helps!

May 19, 2008 at 2:55 pm
(37) JaneD says:

One more thing I would add is this — if you can stick with the Retin A routine you will get a payoff in that most likely, you won’t need any other products. A good cleanser, sunscreen, and Retin A and you are golden. (Maybe a moisturizer for special circumstances – like a Minnesota winter?) If you buy the product in Canada you can get it at a significantly reduced amount. My prescription strength purchased at the local Walgreens was going to be $180 a tube. I bought 3 tubes of the .1% cream (NOT generic either) at Granville’s for $56 TOTAL. That’s a major WOW in my book!

May 19, 2008 at 2:59 pm
(38) JaneD says:

I almost forgot — while you are peeling and going through the transition phase, be extra gentle to your skin when cleansing. Don’t pick at it or scrub it hard to remove the peeling skin. You may find some of the skin will slough off when you are in the shower and you have a significant amount of moisture on your face (I can kind of rub my face with my fingers and the peeling skin will ball up and come off). Any other scrubbing will just irritate things and prolong your pain. I also sometimes use some plain vegetable glycerin on my face (mix with water) to dab on and control the peeling too. Just keep it simple and don’t complicate matters with a ton of different products that might irritate you. You can get food grade natural vegetable glycerin at most health-food stores. It is a great moisturizer all over too!

May 19, 2008 at 3:50 pm
(39) JaneD says:

Okay – I swear this is the last post. The lotion I used to use with Retin A was Complex 15. I have never used another moisturizer like it – you can still get it at drugstore.com. It is WONDERFUL, light and so effective. My derm told me about it and he was right on! (That was back in the day before derms tried to sell you their own lines of potions at a premium!)

May 19, 2008 at 4:57 pm
(40) donnam says:

I am just starting to use renova and really want to order from either the canadian pharmacy or the pharmacy in mexico because of the price. However – I am really afraid of the regulations or lack there of I should say – this is something I am putting on my face.

May 31, 2008 at 11:06 am
(41) jcook says:

I have just discovered this site and I’m so glad! I’m 58 and just started trying to research skin care for the first time in my life (I started in December ‘07). I am using retin a 0.1% that I buy from http://www.medsmex.com. I cannot afford it from my pharmacy–. you do not need a prescription. It costs $36 including shipping.

I highly (also) recommend http://www.cosmeticscop.com–Paula Bedoun has done amazing research.

I have not heard of the copper peptides and will go looking :)

I have bad sun damage–and have only been using the retin a for 4 mo now–and don’t ’see’ a lot of difference–but can feel a change in my skin. But–I know i’m way late in starting this. I’ll continue because I know it’s the best treatment for my skin—aside from constant sunscreen with UVA and UVB protection! :)

Good luck to all.

jcook

May 31, 2008 at 11:22 am
(42) jcook says:

One question–could someone tell me which copper peptide product to use–and exactly how to use it with the use of retin a? –and where’s the best place to buy the cp product? thanks
jcook

June 2, 2008 at 8:01 pm
(43) Suzanne says:

jcook..I bought a tube of Retin-A a few months ago while in Mexico but am afriad to use it..is 0.1 strong? That’s the strength I purchased as well. What kind of reactions did you experience if any?

June 5, 2008 at 4:08 pm
(44) redsky23 says:

Retin-A is such a wonderful product to be use,I will never stop using it.This cream was recommended by my family doctor.He has been using it for more than 10 years.He’s in his late 50’s but looks rather like early 40’s.As for myself, I have been using it for 3 years,its works very good in blackheads and wrinkles on my face. You need to be patience to let it works on the skin. You are sure to see good results after 6 months to 12 months. Over these 3 years I am using Retin-A 0.05% and it proved good results. I came to know about Micro Retin-A recently, I wish to know more and the different between these both products.

June 7, 2008 at 9:25 am
(45) jcook says:

Suzanne–I have not had any problem with that strength–but you might at first. If you pull up sites about how to use Retin A (www.cosmeticscop.com is excellent–go to Learn on her home page)–they will all say to start out using it only every 3rd day or so. And always use only a pea sized amount for the entire face. I am also using an AHA product before I use the retin a. I know–you only have no choice in strength when you order from the Mexico site. Go slowly–if you experiece lots of redness and irritation–back off. But–do go to the site I gave you–or just search Retin a-side effects online. Good luck!

jcook

June 7, 2008 at 9:28 am
(46) jcook says:

Go back to DEc 26 at 12:11 to what Penny says. She gives a good explanation about Retin A Micro

July 7, 2008 at 9:35 am
(47) Rose Brantley says:

I’ve been using Retin A since 1989 when I had adult acene. I’ve seen no side effects. I have great skin. No wrinkles and I’m in my 60’s.

July 8, 2008 at 12:37 am
(48) Jaz says:

I am 25 and have used Retin A on occassion (not for acne) for smooth skin. Is it bad to use the cream at my age? I apply sunscreen every day as I live in Arizona.

July 16, 2008 at 12:23 am
(49) becky says:

I just started using Retin a. Should I use a moisturizer while using this product? Or is it better to let the skin dry out? I live in DRY Colorado and have to use a moisturizer at least twice a day. Will the moisturizer cancel out the effects of the retin a?

July 18, 2008 at 2:33 pm
(50) SuSu says:

I am 60 and have used Retin-A since my 30’s! The dermatologist who prescribed it said to use it ‘FROM NOW ON” and I have! I had two facials done recently and both times was asked what I use on my skin…..and told that my skin was in remarkable condition for someone my age. I use soap & water and .1% every night….a small amt. because of the cost. It is the ONE product I will not do without, however, because I KNOW it works. my dermatologist said to even use it under my eyes…..after years of use, I have no redness or problems with any type of irritation. I had a good deal of acne even into my 30’s…..and had too much sun exposure from being a lifeguard for many years….so to be complimented on my skin now makes me feel great….but I have to give the credit to Retin-A. Now TELL me how safe the Canadian site “Granville” is that I have read about.

July 19, 2008 at 6:05 pm
(51) DL says:

I have just begun to use Retin-A. I have been using it on the sun damage on my arms for the past two weeks. So far, no irritation, but I know that the skin on the arms is very different than the face. A friend of mine says to decrease irritation on her face, she first applies lotion to her face, lets it dry for 30 minutes and then applies a pea size portion of the retin-a to her face. I would like to try this, but this application is different than what the manufacture recommends. Has anyone applied retin-a in this manner?

July 20, 2008 at 1:29 pm
(52) Ellen says:

Well I just rec’d my first order of Retin-A cream from medsmex.com I paid $16.95 for a 40 gm tube of .05% strength. I’m 52 and unfortunately just beginning with Retin-A. I’ve been using Prevage MD for about 6 months and now will try these in combination. Medsmex charges $10 flat shipping rates and I got my order in about 4 days (I’m in California). Not bad plus I was able to order my dogs allergy meds too for $3.48 each!

July 21, 2008 at 6:04 pm
(53) Manon says:

I have been using Retin-A for the past 14 years, I am now 48 years old going on 34 (again):)
It’s the best beauty product I have ever used in my life. I don’t know the cost in the US, but here in Canada it’s sell for 30$ (25) which is more than affordable.

July 21, 2008 at 11:47 pm
(54) shona says:

hai jenny,

m jus 28 years is it safe to use Retin-a my skin is vry sensitive…..pleazzzzzzzzzzzzz suggest me. and from where can i buy it…….m from india

July 28, 2008 at 9:11 pm
(55) sasse1kc says:

My dermatologist prescribed it when I asked what I could do about some of the wrinkles I am getting (I am 40). She asked “Are you using Retin-A yet?”, as if everyone does. :) It is for cosmetic use only, obviously, so insurance does not cover it, but it is less expensive than a lot of the OTC options out there that don’t even work. I have only been using it for a few months but can tell a difference – can’t wait til it’s been a year, want to see how it improves my skin.

Anyway, my point is, ask your dermatologist for it, I would be surprised if they would not give you a prescription (barring any health conflicts).Good luck, ladies, and stay gorgeous!

August 5, 2008 at 4:33 pm
(56) Mary says:

Retin-A is a magnificent product! I am an Aesthetician and prescribe it to patients all the time. I just began using it myself last week, and so far am pleased.
If you don’t have/want a Dermatologist, go to a Med-Spa! They will have Obagi, so they will have the Tretinoin. It is not necessary to get a prescription with all the Med-spas around! It is safe to use, and the nurse or Esthetician can guide you to the proper application.

August 8, 2008 at 12:59 pm
(57) Rachael says:

I’ve used retin-a for about a year now. I’m 37 and get id’ed for beer, people are astonished to find out my age..and this all started after I began using this stuff. My skin is so acclimated I can just put 2 pea size portions on every night and never any burning or redness.I did suffer for almost 4 mos with peeling and redness though before it got to this point. I will never,ever go without. And I no longer sink lots of money into useless creams and potions. I do use University Facelift cream though in the winter..that stuff is awesome too.

August 21, 2008 at 2:30 am
(58) Lara says:

Hi, I just started using Retin A micro 0.04% and I am 39. I get the adult cyst hormone acne and the blackheads as well. I have sun damage on my chest so can I use the retin A micro on my chest? Does anyone here use it on their neck and chest as well. I have been told that long term use of retin A thins the skin and causes little broken blood vessels? Is this true? I was using Tazarac but I was told that is the harshest of retin a’s. So they said to switch to retin A Micro is this true? If anyone can help with my questions I would appreciate it so much. Thank you.

September 8, 2008 at 2:07 pm
(59) Lynn says:

I LOVE this website. I have been using Renova .25 & .5 for many years and EVERYONE says I look at least 10-15 years younger. I’m 52 and look in my late 30’s – or so I’m told. For normal day to day, I use .25 daily, but sometimes when I need a little extra umph, I switch to .05 – like when I need a brown spot that needs an extra push to disappear. I don’t have one wrinkle and even though I don’t put anything under my eyes, I do put a little dot on the crow’s feet and it definitely helps – The crow’s feet never goes away 100%, but a tremendous amount is gone. For me, I don’t need any exra moisturizer.. it is already in the Renova. All I use is Renova and Neutrogena Dry Touch Sun Block 55. I tried putting it under my eyes, and I didn’t like the results.

I do have 2 questions though. What is the difference between Retin-A and Renova?

The next question is..this is silly but.. I’m 52 and even though my face is great, I’m starting to get that soft, extra, saggy skin below my chin and on my neck.. Does anyone have any recommendations to get rid of it?

September 13, 2008 at 11:59 am
(60) Randall651 says:

One of the most famous plastic surgeons in NYC told me about two female patients from South America. They were sisters in their mid-30s. The doctor told me the women had the most beautiful skin he’d ever seen and he’s seen thousands of women as patients. He asked them what skin care they used. They told him that as young women they had acne and that they had been using Retin-A for about 20 years. The doctor tried it on himself but overdid it and his face turned all red. You have to ramp up slowly.

September 16, 2008 at 9:39 pm
(61) Bill says:

Iv’e been using Retin-a for about a year now for acne and have had pretty good results. I’m 21 and have had acne for about 4 yrs. The problem is that i went on a cruise when i started using it, my sunscreen washed off and i got pretty burnt about 8 months ago. I’m worried that i damaged my skin for good. I also heard that Retin-a can give you broken capillaries on your face, is this true or are these people way off? Thank you.

September 17, 2008 at 10:35 pm
(62) Salty says:

I love Retin-A. I have acne prone skin and it really smoothes it out. I have used it for years and buy all of mine from Mexico. My mom goes once a year to stock up on drugs. I’ve had very good luck with it, at a fraction of the cost. I have neglected my neck and am now consistently putting it on at night. My neck didn’t look nearly as good as my face, so I’m looking forward to the improvement.

September 26, 2008 at 10:24 pm
(63) Stacey says:

So whats the verdict on Bill’s question. Has anyone else ever noticed broken capillaries from retin a because im starting to notice some small red veins near my eyes and nose. Is this from using retin-a for 2 years?

October 11, 2008 at 3:48 pm
(64) Ozlem says:

I was wondering if it can be used on the neck area. How often do you put it on? My doctor prescribed a 5 day rotation use at the beginning (1/2 hrs. on first day, 1 hr. 5 days later, etc.)I just wondered if it’s the same with everybody. Thanks.

October 21, 2008 at 10:06 pm
(65) Valerie says:

I’ve been doing quite a bit of research about anti-aging creams and it seems that Retin-A can be a bit rough on your skin. It can also make your skin more sensitive to the sun.

I found this really interesting site that talks about different wrinkle creams and they have a page that tells all about the ingredients and what they do. The part that really caught my attention was about Ascorbyl Palmitate. It seems that Ascorbyl Palmitate has similar results to Retin-A, but without the side effects.Anyway here is a link to the page that talks about Ascorbyl Palmitate. Anti-Wrinkle-Reviews.net/secret.php

October 22, 2008 at 10:58 am
(66) beauty says:

I was at a wedding this weekend with a prominent NYC plastic surgeon who asked me about my favored beauty products. I told him Retin-A was my hands-down favorite and he said, “Oh yes, Retin-A is the best.”

Despite all the new lotions and potions and lasers over the years, Retin-A still comes out near the top and is on the list of so many prominent dermatologists. It’s a miracle worker as far as I’m concerned.

Yes, it can be rough on skin initially and yes, you have to be careful about the sun while on it. But staying out of the sun is the one true way to prevent wrinkles.

People who are unsatisfied with Retin-A products tend to give up on it too quickly due to the initial peeling and redness. It takes up to 6 weeks to see real results and 6 months for fine lines to start disappearing.

Julyne

November 5, 2008 at 1:58 am
(67) colette says:

My doc TOLD me to use it under my eyes and around my lips..just be careful and don’t use a lot. With Retin A a little does go along way. Also, I mix a little face cream with it (as another person mentioned). It keeps you skin from becoming too dry. Most docs will prescribe, for wrinkles–, although it was originally prescribed for acne.
Colette

November 16, 2008 at 11:29 pm
(68) liverpool says:

Re: question 42- I’ve been using tretinoin (retin A) for about 2 months. After applying it, I wait about an hour and apply NEOVA ( a copper peptide product ) to the driest areas. Has anyone else tried this ?

November 17, 2008 at 12:00 pm
(69) Ollie says:

I have been using .05% for a couple weeks. I wash my face at night and slather an olive oil and cocoa butter cream all over my face. I wait about half an hour then I dot a pea size amount all over my face and blend. LET YOUR FACE DRY AND DONT USE ANY MORE THAN A PEA SIZE! I did that only 2 times and my face was tight, burned, peeled and a little swollen for over a week! This “scare:” is why I out the moisturizer on first. Also, don’t put it on your lips – it makes them thick and peel beyond belief – this coming from a girl with perpetual chapped lips.

I am interested in the copper peptide combination. anybody?

November 17, 2008 at 12:58 pm
(70) liverpool says:

I would think that putting moisturizer on before the retin a would seriously inhibit its effectiveness. I’m wondering if putting it on after the retin a slows down the action of the retin a. I’d like to continue using the
Neova because it corrects loss of elasticity and prevents “sagging” (those lovely Howdy Doody lines).My daytime regimen is vitamin c based and wouldn’t combine well with the copper peptides.
Any thouhts , anyone?

November 19, 2008 at 12:00 am
(71) liverpool says:

Me again. Does anyone apply a moisturizer after putting on the retin a ? If so , have you found this method to diminish the effectiveness of the retin a ?

November 19, 2008 at 12:22 am
(72) beauty says:

Liverpool,

The best person to ask, of course, would be a dermatologist who’s studied the effects of retinoids. But I can speak to my own experience and what I’ve found in research….

I’ve been using Retin-A for years and because it is so drying (Renova is more moisturizing, but I get Retin-A so cheap in Mexico, it’s worth it to me), I always use moisturizer before or after and I see no difference.

I’ve seen articles where it’s recommended to use Retin-A with moisturizer. I think your skin soaks it up no matter what and it’s going to work no matter what else you use.

Hope that helps,
Julyne

November 19, 2008 at 9:51 pm
(73) liverpol says:

Thanks Julyne! I did,of course, ask my derm these questions and he felt that moisturizing would have minimal or no effect.
Still, it’s always good to talk to people who have actually tried something . I also use plain tretinoin for the savings.
Thanks again for your input.

December 16, 2008 at 5:20 pm
(74) nicholette says:

I tried ordering Retin-A online through Granville Pharmacy in Canada and was told that I need a prescription. I got the impression from the blog that you did not need prescription to it online from granville in Canada and Medsmex in Mexico. Help Please.

December 17, 2008 at 12:25 pm
(75) Andrea says:

I disagree. I used Renova for about a year. I didn’t see noticeable results with it. In fact, after awhile it made my skin irritated and sensitive. It also made my skin flakey which is tends to do since it sloughs the dead skin off your face. Keep in mind I wasn’t slathering it all over my face either. It’s not a wrinkle remover. In fact there is no wrinkle cream on the market that will remove your wrinkles. They are all scams and I’ve tried a few of them to prove it. Retin A or Renova works well for some people but not everyone. I wouldn’t waste my money on it again. Botox injections is the only thing that takes significant wrinkles away.

December 28, 2008 at 9:07 pm
(76) maureen stehle says:

In my last comment (which I just reread),I was a little unclear.My derm said that using moisturizer after applying the retin a would not diminish its effectiveness. He did suggest waiting a 1/2 hour before applying the moisturizer.
Andrea, retin a is not a scam. I have been using it for just short of 4 months and the difference is incredible. I too had issues with flakiness and dry skin , but I realize now that it was my own ineptitude.
To anyone out there who is considering trying tretinoin or retin a – DO IT ! You’ll be glad you did.
Liverpool

February 12, 2009 at 12:51 am
(77) Caroline says:

Does anyone know if you can use OTC Retinol while breastfeeding? I am using that now but am concerned since it is a Vit A derivative. How could it harm the baby?

February 19, 2009 at 7:47 am
(78) Dan says:

I had severe acne with scarring as a teenager, lived in the Virgin Islands where I had WAY too much sun exposure, and now live in Colorado which is a very dry climate. I’m of Scandinavian heritage and fair to boot! I’m now 52 and my dermatologist has me using Retin-A and CeraVe lotion. It’s been 4 months, and things have come along nicely, though initially my face was very red and flaky. Do check out CeraVe (I have no affiliation with the company). It’s available at walgreens and is a miracle! As a consultant in the medical profession, it’s important to look my best. Retin-A works!

February 27, 2009 at 4:00 pm
(79) Laureli says:

Just started using rentin-a (Trentinoin) @ 0.025%, 45 grams to help with wrinkles on my face and neck. I have used it two nights in a row and do not have redness, peeling or feel burning or have any negative results at all. Does anyone think that this dosage is not STRONG enough for me or will the burning, redening and peeling effects eventually come on with more usage at this current dose? I am so wanting it to work on the slight lines and wrinkles I am starting to see at age 45!

February 28, 2009 at 11:52 am
(80) Maggie says:

Hi, I just got some Renova while on vacation and plan to start using it in a few days. My skin is on the sensitive side so I got the .025 and .05 so hopefully I can increase the dose when I build some tolerance. I have a couple questions I was hoping someone could answer. Directions say a pea size amount– that seems like such a small amount to be able to spread out over my whole face especially is my face is dry… any suggestions? Also, since Renova will make my skin peel is it worth it to try and use a self tanner (for faces) during the day? With summer coming I was hoping to have some kind of color besides red and peeling… any suggestions would be most appreciated! Thanks

March 1, 2009 at 10:19 pm
(81) Susan says:

Maggie, I’m 41 and it’s been exactly 3 months since using Renova at 0.02%. At night I cleanse my face, allow 20 minutes to dry, apply pea-size to face including careful application under eyes and crows feet area. I also use some on my neck. You will get even coverage with experience. Just try to dab it uniformly. Then I wait exactly one hour before moisturizing. I can’t believe how incredibly great my face looks! All of my sunspots and sun damage around and above my cheeks are completely gone. My skin is as soft as a baby’s skin and my pores are small. I used to have wrinkles across my neck but the Renova tightened my neck and it looks great. I took before and after pictures and was amazed with the transformation in 3 months time. I do however have to be careful of the sun. If I don’t wear sunscreen my skin will burn and peel. I wear a hat and I use a sunscreen product called SkinCeuticals SPF 30 recommended by my dermatologist every morning, pea sized amount. It doesn’t irritate the skin like some sunscreens do. It has zinc oxide which makes your skin a little white until it gets absorbed. Here’s my solution for facial color, because now I notice my face is a nice creamy color, but the rest of me is tan. I either apply a self-tanner, or use foundation. A make-up professional at a cosmetic counter helped me select a foundation that matched the rest of my skin. (Estee Lauder Nutritious line $30). If I’m investing time and $ in my face, I might as well paint that canvas beautiful.
Dan, I also use the CeraVe cleanser and lotion, as well Vanicream (ugly name but great product) – no irritation whatsoever.
I also use Botox for my forehead wrinkles. They have all disappeared.
Hope this helps and good luck everyone!

March 3, 2009 at 1:43 am
(82) Susan says:

I think I solved my facial lack of color issue after applying the Skin Ceuticals sunscreen. Blend your pea size amount of sunscreen with a small dab of foundation to your face and neck. A simple time saver!! And it looks natural with the rest of my skin tone.

March 3, 2009 at 6:11 am
(83) Bubbles says:

I was lucky enough to have been prescribed Retin A for pretty horrible acne at the age of 16. I have used it on and off since then. (I’d go off it for a couple of months at a time, most years since then). I will be 50 in a month and people think I am 35. Of course, the exercise helps too, but I look great and I know it and thank you, Retin A. A few tiny lines under my eyes these days, like most 35 year olds! Another trick is to use an AHA in conjunction. During the day. But I only do this in winter because the spf in makeup is okay in winter but not adequate in summer and so the AHA is discarded in favour of a 30+ sunscreen. Wish I’d used Retin A on my arms.

March 4, 2009 at 10:22 am
(84) Maggie says:

Susan thank you so much for all the info! Your success is an inspiration. Okay here is another question… the wrinkles that bother me the most are the ones I have around my mouth. Not the ones that come down from the nose but the ones that turn down from the corners of the mouth like a frown. I hate those!! Has anyone had luck with rentin-A for those types of wrinkles?

March 10, 2009 at 4:56 pm
(85) Maggie says:

I’ve been using Renova for three months and still have tremendous peeling. I’ve always had dry skin. Is that contributing to the peeling? I use a teeny tiny amount and have been using moisturizer about 30 minutes after application. I’ve also noticed that my skin peels in areas that were not touched by the Renova. Thoughts?

March 11, 2009 at 6:10 pm
(86) monica says:

please can someone tell me where I can buy vegetable glycerin in South Africa?

March 17, 2009 at 10:33 am
(87) Ces says:

Hello Everyone, I am glad lots of people out there share the same experience as I do. I have been using Retin A for the last 20 years since I was 28. I dont use it all year round, I use it 3 months in a row and then stop for the next few months and use it again when I feel my skin needs rejuvenating. I love it and never will stop using it. I used to work for a Dermatologist that mixes this product and I got to learn how to make it and where to buy the active ingredient. So guys if you are interested, I have a Retinoic Acid at .05% strength enhanced with lactic acid and it works like magic. I sell this product only to friends and their friends and their friends. So if anyone interested, send me a buzz at corina@naturevine.com.

March 17, 2009 at 10:40 am
(88) Ces says:

Hi all, my other email address is beautyx@bigpond.net.au if you guys want to get the Retinoic Acid I make as a beauty therapist. It’s a great product.

March 18, 2009 at 9:17 am
(89) ron says:

Hi guys thanks for all this good info. Im 35 and look about 25 but wanna start something now for my skin. Problem is i work outside and that seems to be a problem if i start retin a. i can wear hats and stuff but sometimes its unavoidable. Is sun block enough?

March 18, 2009 at 1:04 pm
(90) beauty says:

Hey Ron,

Yes, you can protect your skin with heavy-duty sunscreen! Just be sure to reapply several times a day and make sure it’s at least SPF 40.

You can skip using it during the summer and use Retin-A or Renova in the late fall through early Spring.

Julyne

March 21, 2009 at 9:07 am
(91) ron says:

Thanks Beauty. What is the best approach to lessen the initial irratation? I have read the above post addressing the issue. What do you think? Every other day and mix it with a moisterizer. or can I start every 3 day and so on. Will that help? Thanks again.

March 23, 2009 at 12:52 am
(92) Moniccha says:

Hi there, i used retin a .025% for 6 months n loved the result..my skin become healthier,younger,n smaller pores..i used to apply Bha 2% frm Paula’ choice before n then applying some moistrzer after retin a..
In my country i pay it only for $3.5 w/ presc

March 23, 2009 at 2:47 am
(93) Moniccha says:

Sorry,i mean without prescription i get retin a .025% 20gr for only $3.5,thank god..btw i’m in indonesia n 32 years old but everyone thought me still in college..
Is it true that 1 tube of retin a is only efective about in a month n we have to change new

March 23, 2009 at 9:37 am
(94) Maggie says:

I’m a week into this and having a lot of irritation. I think I will skip tonight. I got irritation on my neck and I didn’t even put the cream there…. odd. Hey does anybody know WHY the skin must be so dry (wait 30 mins)before application? Just curious. One night I only waited ten mins as I was really tired and I am wondering if that set off all this irritation? Thoughts anyone? Also what have you ladies used to calm irritation in the early days of getting used to retin-a? My moisturizer is burning a bit. It’s Eucerine Redness Relief.
Thanks!

March 24, 2009 at 4:02 am
(95) Moniccha says:

Hi maggie..maybe your cleanser or another skincare make irritation getting worst..i only used a mild cleanser from paula’s choice its really helped,no toner or astringent,alcohol free,moist that wont clog pore..etc

March 31, 2009 at 6:18 am
(96) Toni says:

I have been using Retin-A-Micro for over 13 years and absolutely love it. I’ll use it as long as I can afford it or live, which ever comes first. For those struggling with the side effects, just get through the first seven weeks!!!! I had read that when I first tried it and it was so true. After seven weeks all the soreness (my face felt like raw meat-although it looked fine) and itching went away. I now can use it (.04% gel) in the morning and evening and it feels just like putting on face lotion.

Hang in there. If you can get through the discomfort the effects are well worth it.

April 6, 2009 at 5:22 am
(97) Harry Axe says:

I look great! I have also been a model for a youth brand and I’m 34!

I love this product!

April 29, 2009 at 3:32 am
(98) cowgirl says:

Hi everyone. I am an avid Retin-a user. I first started in my early 30’s – for adult csytic acne(which my derm said I will not grow out of) and have been using it for over 20 years. If you have acne when you start…hang in there-it WILL get worse and then clear up! I also used it in combination with Azelex cream(for acne). I continue to use R-a almost every night…and I do sometimes add a moisturizer, still great results. I have ordered from Canada for years-I receive EXACTLY the same tube that I received in the states. I also order from Mexico-same tube. My tip: start using it early and keep on using it & USE SUNSCREEN! Canada price-40 gr tube-approx $40. Mexico-$30.all depending on strength. So glad this site is here-thanks for sharing. Happy skin…happy faces

April 29, 2009 at 8:37 am
(99) Stephen says:

I’m 58 male and wish I knew how effective this was. I take Cyprenil for 17 yr which is a deprenyl product that extends life by 50% and I can say I feel physically like 21, no aches, pain, disease and sleep perfectly. But my skin has aged with wrinkles because I work outdoors for 40 yrs. My skin is taught and no sags. I don’t think retin a will eliminate all my wrinkles but I have discovered a fantastic chemical peel that literally reduces deep line wrinkles almost 95% or more. I will get this 1st then continue with retin a. The peel is called the Hetter Peel. Check out the pictures of before and after.
http://www.hetterpeel.com/whychoose.html
it’s been around 9 yr but is still very rare.
Cyprenil source http://www.cyto-pharma.com/cyprenil.htm this stuff extended life in rats and dogs when given to the animals who were the equivalent of 60 yr old in human terms and it still worked. Don’t drink coffee with it. The only side effect which causes a stiff neck.

May 17, 2009 at 10:24 am
(100) Curious says:

To the Author:

Out of curiosity, what is the name of the brand of Tretinoin that you get from Mexico? Is it just a generic name such as Retacnyl? I see that you can order it rather cheaply online however I don’t know how safe that is? Is there a specific location in Mexico that you trust to get your medicine from? If so, where?

Thanks for the help!

June 6, 2009 at 10:58 pm
(101) james says:

i’m 33 now with some sun damage and some acne again. I used retin a when i was 15 years old for a couple of years and it worked great then. now as my skin is older and has been exposed to the sun it is showing. So my derm put me back on retin a micro. Been using it for a week and have some redness and irritation, but i can hang in there, because i know the results will be worth it.

July 8, 2009 at 2:40 pm
(102) M Wallace says:

Hello All! Retin A is a GREAT thing that helps reduce acne, soften wrinkles, exfoliates, reduces big pores and eats away blackheads. I think alot of people stop using it when they see there skin getting red and flaking, but this is pretty normal. Just know in a few weeks the redness will stop and if it doesn’t, make an appt with your doctor.I would suggest using it every other night, instead of every night if this happens to you. Only use a pea size amount for your whole face because it is strong stuff. You can even mix that small amount with your moisturizer if your skin gets too irritated. Oh and remember to where a good facial sunscreen EVERYDAY or your face will fry! As far as putting it on stretch marks, the only thing that a doctor can do is cut them out OR if they are red, there are lasers that can lighten them a little. Sucks I know. Good luck everyone!

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